Background  Lens coloboma is a rare congenital disorder of crystalline lens characterized by notching of the equator of the lens. Coloboma can occur in isolation or with other ocular malformations.
Case  We describe 5 cases of lens coloboma  associated with some ocular malformations.
Observations  One case was without associated ocular anomalies. One case included iris and choroid coloboma; another included total cataract; and a fourth included lens dislocation. The remaining one included aniridia . The pathogenic mechanisms and relationship of the ocular malformations is discussed.
Conclusions  Lens coloboma can be associated with other ocular malformations, such as iris coloboma, choroid colobma, localized or total caratact.